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Which cells are primarily targeted and destroyed by HIV?

Biology

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Answer

D

The correct answer is d).

HIV (Human Immunodeficiency Virus) primarily targets and destroys cells that express the CD4 receptor on their surface. These cells are crucial for the proper functioning of the immune system.

  • a) CD8 T lymphocytes are cytotoxic T cells. While their function can be affected by HIV infection, they are not the primary cells directly destroyed by the virus.
  • b) Endothelial cells line blood vessels and are not the main target of HIV.
  • c) This option is blank.
  • d) CD4 T lymphocytes (also known as T-helper cells) are the main target cells for HIV. The virus binds to the CD4 receptor and co-receptors on these cells, enters them, replicates, and ultimately leads to their destruction. The progressive loss of CD4 T cells is a hallmark of HIV infection and leads to immunodeficiency.
  • e) Neutrophils are a type of white blood cell involved in innate immunity and are not directly targeted and destroyed by HIV.

The final answer is d. CD4 T lymphocytes.\boxed{\text{d. CD4 T lymphocytes.}}

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