Fresh day, fresh solve.
Here are the answers to the multiple-choice questions:
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D. Concentration of disinfectant
- The absorption of a substance from intact skin is directly influenced by its concentration. A higher concentration creates a steeper concentration gradient, leading to increased absorption.
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B. Halothane
- Halothane is a volatile inhaled anesthetic. Volatile anesthetics are primarily eliminated from the body unchanged via the pulmonary (respiratory) route.
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C. Conjugation with endogenous substrates increase aqueous solubility
- Conjugation reactions (Phase II metabolism) involve attaching polar endogenous molecules (like glucuronic acid or sulfate) to the drug. This significantly increases the drug's aqueous solubility, making it easier for the kidneys to excrete.
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A. Prolonged therapeutic effects
- When a drug binds to plasma proteins, it becomes pharmacologically inactive and cannot be metabolized or excreted. This binding acts as a reservoir, slowly releasing the free, active drug, thereby prolonging its presence in the body and its therapeutic effects.
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B. Saxagliptin
- Saxagliptin is a dipeptidyl peptidase-4 (DPP-4) inhibitor, a class of drugs used to treat type 2 diabetes by increasing incretin levels.
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D. Carbidopa
- Carbidopa is a peripheral DOPA decarboxylase inhibitor. It prevents the breakdown of levodopa into dopamine in the bloodstream before it reaches the brain, allowing more levodopa to cross the blood-brain barrier and be converted to dopamine in the central nervous system, thus prolonging its action and reducing peripheral side effects.
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B. Ephedrine
- Ephedrine is a sympathomimetic amine that causes vasoconstriction in the nasal mucosa, reducing swelling and congestion. It is a classic nasal decongestant.
Drop the next question.