What is the relationship between coronary arteries disease, low cholesterol and high cholesterol

The relationship with cholesterol types is crucial:

• High cholesterol, specifically high levels of LDL (low-density lipoprotein) cholesterol, is a major risk factor for CAD. LDL is often called "bad" cholesterol because it contributes to the formation of plaque in the arteries, leading to their hardening and narrowing.
• Low cholesterol can be interpreted in two ways:
  • Low HDL (high-density lipoprotein) cholesterol is also a risk factor for CAD. HDL is considered "good" cholesterol because it helps remove excess cholesterol from the arteries, preventing plaque buildup. Therefore, having low HDL reduces this protective effect.
  • Having low total cholesterol (which would include low LDL) is generally beneficial as it means less material for plaque formation, thus reducing the risk of CAD. The key is the balance between high LDL and low HDL.