TEST Questions Advanced Molecular biology BCH432 (Muhammad Bawa) What is a Plasmid? Draw the structure of a plasmid showing basic restriction sites Briefly describe the five (5) types of plasmid give a brief history of Joshua Lederberg comment on the following : (1) colicinogenic (or Col ) factors (ii) colicins (iii) R factors, (iv) an episome Discuss the mechanisms for the exchange/ transfer of genetic materials What is bacteriophage? Describe the morphology of Bacteriophage Describe the lytic and lysogenic cycles of bacteriophage Discuss the principle of chemotherapy and mechanism of drug resistance Differentiate between Recessive and Dominant Mutant Alleles Differentiate between mitosis and meiosis Outline the mechanisms of genetic variation What is mutations? Discuss the types of mutations Comment on DNA Cleavage by Restriction Enzymes Describe the Construction of cDNA Library DNA Detection by Membrane Hybridization Define the following terms (i) genetics (ii) Gene (ii) Exon (iv) introns Griffith (1928) and Avery (1944); worked on S- forms and R-forms of the strep Pneumonia, describe how DNA was confirmed to be responsible for transformation