Here are the signs, symptoms, control measures, and treatments for each disease: Congenital Syphilis / Secondary Syphilis* Signs and Symptoms: Congenital Syphilis:* Rash (often on palms and soles), enlarged liver and spleen, bone abnormalities, anemia, jaundice, snuffles (runny nose). If untreated, can lead to developmental delays, seizures, and deafness. Secondary Syphilis:* Widespread rash (often on palms and soles, but can be anywhere), fever, swollen lymph nodes, sore throat, patchy hair loss, muscle aches, weight loss, fatigue. Control Measures: Congenital Syphilis:* Routine syphilis screening and treatment of pregnant women during prenatal care. Secondary Syphilis:* Safe sex practices (condom use), regular STI screening, partner notification and treatment. Treatment: Congenital Syphilis:* Penicillin G (dosage and duration depend on age and clinical findings). Secondary Syphilis: A single dose of intramuscular benzathine penicillin G*. Gonorrhea* Signs and Symptoms: Males:* Painful urination, pus-like discharge from the penis, pain or swelling in one testicle. Females:* Increased vaginal discharge, painful urination, vaginal bleeding between periods, abdominal pain. Many women are asymptomatic. Rectal:* Anal itching, discharge, bleeding, painful bowel movements. Throat:* Sore throat (often asymptomatic). Control Measures: Safe sex practices (condom use), regular STI screening (especially for sexually active individuals), prompt treatment of infected individuals and their partners. Treatment: A combination of injectable ceftriaxone and oral azithromycin or doxycycline*. Primary Syphilis* Signs and Symptoms: A single, firm, round, painless sore called a chancre* at the site of infection (genitals, anus, mouth, or lips). Swollen lymph nodes near the chancre. Control Measures: Safe sex practices (condom use), regular STI screening, partner notification and treatment. Treatment: A single dose of intramuscular benzathine penicillin G*. What's next?