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What are the definitions of diffusion, filtration, transcytosis, and diapedesis as transport mechanisms across capillary membranes?
Biology
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Here are the definitions of the transport mechanisms from the text:
- Diffusion: Water-soluble substances (e.g., glucose, Na, Cl, K) diffuse through capillary pores, while fat-soluble substances (e.g., O) diffuse across the entire capillary wall. Diffusion of fat-soluble substances and O is normally greater and faster than water-soluble substances.
- Filtration: This is the process where fluid and dissolved substances are forced through the capillary membrane due to a difference in hydrostatic pressure. The amount of fluid filtered is proportional to the pressure difference, capillary surface area, and capillary permeability.
- Transcytosis (Cytopempsis or Vesicular Transport): This is the mechanism for transporting large molecules across the capillary membrane. Molecules are transported into endothelial cells by endocytosis, followed by exocytosis on the interstitial side. Small amounts of protein typically leave the bloodstream this way.
- Diapedesis: This is the mechanism of transport of a whole cell across a capillary membrane, such as leukocytes leaving the bloodstream towards a site of inflammation.
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