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The female parent has Blood group O, so her genotype is ii. She passes an i allele to all her offspring.

Biology

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1.5.1

  • a) W: The female parent has Blood group O, so her genotype is iiii. She passes an ii allele to all her offspring. One child has Blood group A, meaning its genotype is IAiI^A i. This child received IAI^A from W. Another child has Blood group B, meaning its genotype is IBiI^B i. This child received IBI^B from W. Therefore, W must possess both IAI^A and IBI^B alleles. The genotype of W is IAIB\boxed{I^A I^B}.

  • b) X: The male parent has Blood group A. Since his mother is Blood group O (iiii) and his father is W (IAIBI^A I^B), his genotype must be IAiI^A i. This male parent and X have a child with Blood group O, whose genotype is iiii. For the child to be iiii, it must have received an ii allele from the father (IAiI^A i) and an ii allele from the mother (X). Therefore, X must carry at least one ii allele. The possible genotypes for X that include an ii allele are IAi,IBi,ii\boxed{I^A i, I^B i, ii}.

1.5.2

Haemophilia is an X-linked recessive disorder. Males have one X and one Y chromosome. If their single X chromosome carries the recessive allele for haemophilia, they will express the disorder because there is no dominant allele on the Y chromosome to mask it. Females have two X chromosomes, so they typically need two copies of the recessive allele to be affected; if they have one recessive and one dominant allele, they are usually just carriers.

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