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What are the normal ranges and key considerations for common blood tests like ESR and Bleeding Time, and what are the risks associated with blood transfusions?

Biology

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Question C (from previous section): Why must the ESR tube be kept perfectly vertical?
Even a slight tilt (3∘3^\circ) can significantly increase the sedimentation rate, leading to a false-positive result.

Station 10: Bleeding Time (IVY vs. DUKE)

  • Question A: Why is the Ivy Method considered more accurate than the Duke Method? Because it uses a standardized pressure (40 mmHg40 \text{ mmHg}) and a standardized site, making it more reproducible.

  • Question B: Name one drug a patient might be taking that would prolong the Bleeding Time. Aspirin (or any NSAID that inhibits platelet aggregation).

  • Question C: What is the normal range for Bleeding Time using the Ivy method? 2 to 9 minutes (ranges vary slightly by lab manual, check your local standard).

Station 11: Blood Grouping Hazards

  • Question A: What is the most dangerous complication of a mismatched ABO blood transfusion? Acute Hemolytic Transfusion Reaction.

  • Question B: Define "Agglutination" and distinguish it from "Coagulation." Agglutination is the clumping of particles (antigen-antibody reaction). Coagulation is the chemical process of forming a fibrin clot.

  • Question C: Why do we use a white tile for the grouping practical? To provide maximum contrast so that the red clumps (agglutinates) are easily visible against the white background.

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