A) Give two (2) differential diagnoses.

Biology

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Here are the answers to the questions:

a) Give two (2) differential diagnoses.

  • Acute Glomerulonephritis
  • Protein-losing enteropathy

b) What is the most likely diagnosis for this patient?
The most likely diagnosis is Nephrotic Syndrome.

c) Mention one bedside investigation you are going to do in order to support your diagnosis in (b) and what will the results show?
Bedside investigation: Urine dipstick test.
Results: It will show +++ or ++++ proteinuria.

d) Mention two (2) other diagnostic clinical parameters for this condition. (add values)

  1. Serum albumin: Less than 2.5 g/dL2.5 \text{ g/dL} (or 25 g/L25 \text{ g/L}).
  2. Urine protein excretion: Greater than 40 mg/m2/hour40 \text{ mg/m}^2\text{/hour} or a urine protein:creatinine ratio greater than 2 mg/mg2 \text{ mg/mg}.

e) Mention any 3 complications of this condition.

  1. Infections (e.g., peritonitis, cellulitis)
  2. Thromboembolism (e.g., deep vein thrombosis, pulmonary embolism)
  3. Acute kidney injury

f) Briefly outline your management plan for this patient.

  1. Initiate corticosteroid therapy (e.g., oral prednisone) as the primary treatment.
  2. Manage edema with diuretics (e.g., furosemide) and salt restriction.
  3. Monitor for and treat complications such as infections and thromboembolism.
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