What is cd4+? in phe
Biology
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In pharmacology, CD4+ refers to a cell surface glycoprotein that serves as a co-receptor for the T cell receptor (TCR). It is primarily found on the surface of helper T cells, regulatory T cells, monocytes, macrophages, and dendritic cells.
The CD4+ molecule plays a crucial role in the immune system by binding to MHC class II molecules on antigen-presenting cells, which helps to activate T cells. In the context of HIV/AIDS, the virus specifically targets and infects CD4+ T cells, leading to a decline in their numbers and a weakened immune system. Measuring CD4+ counts is therefore a key indicator of immune function in individuals with HIV.
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