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Determine the father's genotype.

Biology

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Answers

2 parts
a

XhYX^h Y

XHXhX^H X^h

c

12 or 50%\frac{1}{2} \text{ or } 50\%

Step-by-step solution

7 steps

Part a· 2 steps

  1. Determine the father's genotype.

    The man suffers from haemophilia, which is a sex-linked recessive condition. Since 'h' represents the allele for haemophilia, his genotype is XhYX^h Y.

  2. Determine the mother's genotype.

    The woman is described as normal, but their daughter, Mercy, is haemophiliac. For Mercy to be haemophiliac, her genotype must be XhXhX^h X^h. She inherits one XhX^h from her father (XhYX^h Y) and one XhX^h from her mother. Since the mother is phenotypically normal but carries the haemophilia allele, her genotype must be XHXhX^H X^h (a carrier).

    The genotype of the parents are:

    • Father: XhY\boxed{X^h Y}
    • Mother: XHXh\boxed{X^H X^h}

Part b· 3 steps

  1. Identify the gametes produced by each parent.

    Mother (XHXhX^H X^h): Gametes are XHX^H and XhX^h.
    Father (XhYX^h Y): Gametes are XhX^h and YY.

  2. Construct a Punnett square to show the genotypes of the offspring.

    GametesXhYXHXHXhXHYXhXhXhXhY\begin{array}{|c|c|c|} \hline \text{Gametes} & X^h & Y \\ \hline X^H & X^H X^h & X^H Y \\ \hline X^h & X^h X^h & X^h Y \\ \hline \end{array}
  3. List the genotypes of the offspring.

    The possible genotypes of the offspring are:

    • XHXhX^H X^h (Carrier female, normal phenotype)
    • XHYX^H Y (Normal male)
    • XhXhX^h X^h (Haemophiliac female)
    • XhYX^h Y (Haemophiliac male)

Part c

12 or 50%\frac{1}{2} \text{ or } 50\%

  1. Determine the probability of a son being haemophiliac.

    From the Punnett square, the male offspring genotypes are XHYX^H Y (normal) and XhYX^h Y (haemophiliac).
    There are 2 possible male genotypes, and 1 of them is haemophiliac.
    The probability of a son being haemophiliac is 12\frac{1}{2}.
    Probability of son being haemophiliac: 12 or 50%\boxed{\frac{1}{2} \text{ or } 50\%}

  2. Determine the probability of a daughter being haemophiliac.

    From the Punnett square, the female offspring genotypes are XHXhX^H X^h (carrier, normal phenotype) and XhXhX^h X^h (haemophiliac).
    There are 2 possible female genotypes, and 1 of them is haemophiliac.
    The probability of a daughter being haemophiliac is 12\frac{1}{2}.
    Probability of daughter being haemophiliac: 12 or 50%\boxed{\frac{1}{2} \text{ or } 50\%}

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