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What are the characteristics of Down's syndrome and how is complementary DNA and mRNA synthesized from a given DNA strand?

Biology

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  1. Answer question 17(a).

    Down's syndrome is a genetic condition caused by an extra copy of chromosome 21.

    a) Characteristics of an individual with Down's syndrome include:

    • Intellectual disability (ranging from mild to moderate).
    • Distinctive facial features such as a flattened facial profile, upward slanting eyes, and a small nose.
    • Short stature and a short neck.
    • Poor muscle tone (hypotonia).
    • A single deep crease across the palm of the hand.
  2. Answer question 17(b).

    The given DNA strand sequence is G-C-C-T-A-G-A-T-C-A-C.

    b) (i) The complimentary DNA strand.
    In DNA, Adenine (A) pairs with Thymine (T), and Guanine (G) pairs with Cytosine (C).
    Given strand: G-C-C-T-A-G-A-T-C-A-C
    Complementary DNA strand: C-G-G-A-T-C-T-A-G-T-G

    The complimentary DNA strand is: C-G-G-A-T-C-T-A-G-T-G\boxed{\text{C-G-G-A-T-C-T-A-G-T-G}}

    b) (ii) The M-RNA strand copied from this DNA portion.
    During transcription, DNA is used as a template to synthesize mRNA. In RNA, Uracil (U) replaces Thymine (T). So, A pairs with U, and G pairs with C.
    Given DNA template strand: G-C-C-T-A-G-A-T-C-A-C
    mRNA strand: C-G-G-A-U-C-U-A-G-U-G

    The M-RNA strand is: C-G-G-A-U-C-U-A-G-U-G\boxed{\text{C-G-G-A-U-C-U-A-G-U-G}}

  3. Answer question 18.

    Phenotypic characteristics selected for modern agricultural purposes aim to improve productivity, resilience, and quality.

    1. Phenotypic characteristics selected for modern agricultural purposes include:
    • High yield (increased production of crops or livestock products).
    • Disease resistance (ability to withstand common plant or animal diseases).
    • Pest resistance (resistance to insect pests).
    • Drought resistance or tolerance to other adverse environmental conditions (e.g., salinity).
    • Faster growth rate or shorter maturity period.
    • Improved nutritional content (e.g., higher protein, vitamin, or mineral levels).
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