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Explain more in simple terms how kidney regulates acid, base balance

Chemistry

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The kidneys play a crucial role in maintaining the body's acid-base balance by adjusting the amounts of hydrogen ions (H+H^+) and bicarbonate ions (HCO3−HCO_3^-) in the blood.

  • When the body is too acidic (low pH), the kidneys secrete more H+H^+ into the urine to remove acid and reabsorb more HCO3−HCO_3^- back into the blood to buffer the acid.
  • When the body is too alkaline (high pH), the kidneys reabsorb less HCO3−HCO_3^- (allowing it to be excreted) and secrete less H+H^+ (or even reabsorb it) to conserve acid.

This selective secretion and reabsorption primarily occur in the distal convoluted tubule and collecting duct of the nephron, ensuring that blood pH remains stable.

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