This mathematics problem involves applying core mathematical principles and formulas. Below you will find a complete step-by-step solution with detailed explanations for each step, helping you understand not just the answer but the method behind it.

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Answer
216 molecules
10.1 Step 1: Substitute into the given equation for . The equation for the number of molecules is . Step 2: Calculate the value. The number of molecules of the drug in the bloodstream 3 hours after the drug was taken is .
10.2 Step 1: Find the first derivative of to determine the rate of change. Step 2: Substitute hours into the rate equation . Step 3: Calculate the rate. The rate at which the number of molecules of the drug is changing at exactly 2 hours is .
10.3 Step 1: To find when the rate of change is a maximum, we need to find the derivative of the rate function, , and set it to zero. This is the second derivative of . Step 2: Set to zero and solve for . Step 3: Verify that this value corresponds to a maximum. The third derivative , which is less than 0, confirming it's a maximum. The value is within the domain . The rate at which the number of molecules of the drug in the bloodstream is changing will be a maximum after .
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10.1 Step 1: Substitute t=3 into the given equation for M(t). The equation for the number of molecules is M(t) = -t^3 + 3t^2 + 72t.
This mathematics problem involves applying core mathematical principles and formulas. Below you will find a complete step-by-step solution with detailed explanations for each step, helping you understand not just the answer but the method behind it.