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Consider albino in Hong Local government where population of the affected individual is 1 in to 100,000, Using Hardy Weinberg formula to calculate 1. Heterozygous 2. Homozygous dominant 3. Recessive allele frequency.
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3 stepsHere's how to solve this genetics problem using the Hardy-Weinberg principle:
The Hardy-Weinberg equations are:
Allele frequencies:
Genotype frequencies:
Where:
- = frequency of the dominant allele
- = frequency of the recessive allele
- = frequency of the homozygous dominant genotype
- = frequency of the homozygous recessive genotype (affected individuals)
- = frequency of the heterozygous genotype (carriers)
Given: The frequency of affected individuals (albinos) is 1 in 100,000. Since albinism is a recessive trait, affected individuals have the homozygous recessive genotype.
Determine the frequency of the homozygous recessive genotype ().
Calculate the recessive allele frequency ().
Calculate the dominant allele frequency ().
Using the allele frequency equation :
Now, let's calculate the requested values:
3. Recessive allele frequency
This is the value of .2. Homozygous dominant allele frequency
This refers to the frequency of the homozygous dominant genotype ().1. Heterozygous allele frequency
This refers to the frequency of the heterozygous genotype ().
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