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What are the effects of paracetamol overdose? A. Kidney stones B. Liver damage C. Diabetes D. Asthma

Biology

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3 steps

The question asks: "Paracetamol overdose causes?"

  1. Understand the effects of paracetamol (acetaminophen) overdose.

    Paracetamol is metabolized in the liver. In therapeutic doses, it is safe. However, in overdose, the liver's detoxification pathways become overwhelmed, leading to the accumulation of a toxic metabolite (N-acetyl-p-benzoquinone imine or NAPQI).

  2. Identify the primary organ affected by this toxic metabolite.

    The toxic metabolite, NAPQI, primarily causes damage to liver cells (hepatocytes). This can lead to severe liver damage, including acute liver failure.

  3. Evaluate the given options.

    • A. Kidney stones: Not a primary consequence of paracetamol overdose.
    • B. Liver damage: This is a well-known and severe consequence of paracetamol overdose.
    • C. Diabetes: Not directly caused by paracetamol overdose.
    • D. Asthma: Not related to paracetamol overdose.

    The final answer is B. Liver damage\boxed{\text{B. Liver damage}}
    One more to go today! Send it over.

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