The following are solutions to genetics questions: a) Name two disorders in humans caused by gene mutation. b) Describe inversion and translocation. c) In mice the allele for

Here are the solutions to the genetics questions:

Question 12:

• a) Name two disorders in humans caused by gene mutation.

  • Sickle cell anemia
  • Cystic fibrosis

• b) Describe the following chromosomal mutations:

  • (i) Inversion: This is a chromosomal mutation where a segment of a chromosome breaks off, flips 180 degrees, and reattaches to the same chromosome in the reverse orientation.
  • (ii) Translocation: This is a chromosomal mutation where a segment of one chromosome breaks off and attaches to a different, non-homologous chromosome.

• **c) In mice the allele for