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Using a metabolic pathway only, describe the biosynthesis of Serine amino acid.
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SECTION A
1a. Using a metabolic pathway only, describe the biosynthesis of Serine amino acid.
Serine is synthesized from 3-phosphoglycerate, an intermediate of glycolysis.
3-Phosphoglycerate dehydrogenase* oxidizes 3-phosphoglycerate to 3-phosphohydroxypyruvate.
This reaction uses as a cofactor.
Phosphoserine aminotransferase* transfers an amino group from glutamate to 3-phosphohydroxypyruvate, forming phosphoserine and -ketoglutarate.
Phosphoserine phosphatase* hydrolyzes phosphoserine to
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