This chemistry question involves key chemical concepts and calculations. The detailed solution below walks through each step, from identifying the reaction type to computing the final answer.
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To solve this problem, we need the prescribed dose per kilogram per day. Since it's not explicitly stated in your current question, I will assume the dose is 60 mg/kg/day, similar to the previous problem. Given Information (with assumed dose): Patient weight: 15 kg Assumed Dose:* 60 mg/kg/day Frequency: Twice daily (BID) Duration: 7 days Suspension strength: 250 mg/5 mL Tablet strength: 500 mg/tablet --- a) What's the required dose per administration? Step 1: Calculate the total daily dose. Total daily dose = Dose per kg per day × Patient weight Total daily dose = 60 mg/kg/day × 15 kg = 900 mg/day Step 2: Calculate the dose per administration. Since the medication is taken twice daily (BID), there are 2 administrations per day. Dose per administration = Total daily doseNumber of administrations per day Dose per administration = 900 mg/day2 administrations/day = 450 mg/administration The required dose per administration is 450 mg. --- b) What is the total volume of suspension required? Step 1: Calculate the total amount of drug needed for the entire 7-day course. Total drug needed = Total daily dose × Duration Total drug needed = 900 mg/day × 7 days = 6300 mg Step 2: Determine the concentration of the suspension in mg/mL. Suspension concentration = 250 mg5 mL = 50 mg/mL Step 3: Calculate the total volume of suspension required. Total volume of suspension = Total drug neededSuspension concentration Total volume of suspension = 6300 mg50 mg/mL = 126 mL The total volume of suspension required is 126 mL. --- c) How many 500 mg tablets are needed to compound this? Step 1: Use the total amount of drug needed for the entire course, calculated in part b. Total drug needed = 6300 mg Step 2: Calculate the number of tablets required based on the tablet strength. Number of tablets = Total drug neededTablet strength Number of tablets = 6300 mg500 mg/tablet = 12.6 tablets The number of 500 mg tablets needed to compound the suspension is 12.6 tablets.