A physician prescribed ciproflaxin for a 15kg child to be taken twice daily for 7 days. You need to compound a suspension with a strength of 250mg/5ml. a. What's the required dose per administration. b. What is the total volume of suspension required c. How many 500mg tables are needed to compound this?

Question

A physician prescribed ciproflaxin for a 15kg child to be taken twice daily for 7 days. You need to compound a suspension with a strength of 250mg/5ml. a. What's the required dose per administration. b. What is the total volume of suspension required c. How many 500mg tables are needed to compound this?

Asked on April 6, 2026Chemistry

This chemistry question involves key chemical concepts and calculations. The detailed solution below walks through each step, from identifying the reaction type to computing the final answer.

Accepted Answer · 2026-04-06T20:26:18.140Z

To solve this problem, we need the prescribed dose per kilogram per day. Since it's not explicitly stated in your current question, I will assume the dose is $60 \text{ mg/kg/day}$, similar to the previous problem. Given Information (with assumed dose): Patient weight: $15 \text{ kg}$ Assumed Dose:* $60 \text{ mg/kg/day}$ Frequency: Twice daily (BID) Duration: $7 \text{ days}$ Suspension strength: $250 \text{ mg/5 mL}$ Tablet strength: $500 \text{ mg/tablet}$ --- a) What's the required dose per administration? Step 1: Calculate the total daily dose. $$ \text{Total daily dose} = \text{Dose per kg per day} \times \text{Patient weight} $$ $$ \text{Total daily dose} = 60 \text{ mg/kg/day} \times 15 \text{ kg} = 900 \text{ mg/day} $$ Step 2: Calculate the dose per administration. Since the medication is taken twice daily (BID), there are 2 administrations per day. $$ \text{Dose per administration} = \frac{\text{Total daily dose}}{\text{Number of administrations per day}} $$ $$ \text{Dose per administration} = \frac{900 \text{ mg/day}}{2 \text{ administrations/day}} = 450 \text{ mg/administration} $$ The required dose per administration is $\boxed{\text{450 mg}}$. --- b) What is the total volume of suspension required? Step 1: Calculate the total amount of drug needed for the entire 7-day course. $$ \text{Total drug needed} = \text{Total daily dose} \times \text{Duration} $$ $$ \text{Total drug needed} = 900 \text{ mg/day} \times 7 \text{ days} = 6300 \text{ mg} $$ Step 2: Determine the concentration of the suspension in mg/mL. $$ \text{Suspension concentration} = \frac{250 \text{ mg}}{5 \text{ mL}} = 50 \text{ mg/mL} $$ Step 3: Calculate the total volume of suspension required. $$ \text{Total volume of suspension} = \frac{\text{Total drug needed}}{\text{Suspension concentration}} $$ $$ \text{Total volume of suspension} = \frac{6300 \text{ mg}}{50 \text{ mg/mL}} = 126 \text{ mL} $$ The total volume of suspension required is $\boxed{\text{126 mL}}$. --- c) How many 500 mg tablets are needed to compound this? Step 1: Use the total amount of drug needed for the entire course, calculated in part b. $$ \text{Total drug needed} = 6300 \text{ mg} $$ Step 2: Calculate the number of tablets required based on the tablet strength. $$ \text{Number of tablets} = \frac{\text{Total drug needed}}{\text{Tablet strength}} $$ $$ \text{Number of tablets} = \frac{6300 \text{ mg}}{500 \text{ mg/tablet}} = 12.6 \text{ tablets} $$ The number of 500 mg tablets needed to compound the suspension is $\boxed{\text{12.6 tablets}}$.

Accepted Answer · 2026-04-06T20:26:18.140Z

To solve this problem, we need the prescribed dose per kilogram per day. Since it's not explicitly stated in your current question, I will assume the dose is $60 \text{ mg/kg/day}$, similar to the previous problem. Given Information (with assumed dose): Patient weight: $15 \text{ kg}$ Assumed Dose:* $60 \text{ mg/kg/day}$ Frequency: Twice daily (BID) Duration: $7 \text{ days}$ Suspension strength: $250 \text{ mg/5 mL}$ Tablet strength: $500 \text{ mg/tablet}$ --- a) What's the required dose per administration? Step 1: Calculate the total daily dose. $$ \text{Total daily dose} = \text{Dose per kg per day} \times \text{Patient weight} $$ $$ \text{Total daily dose} = 60 \text{ mg/kg/day} \times 15 \text{ kg} = 900 \text{ mg/day} $$ Step 2: Calculate the dose per administration. Since the medication is taken twice daily (BID), there are 2 administrations per day. $$ \text{Dose per administration} = \frac{\text{Total daily dose}}{\text{Number of administrations per day}} $$ $$ \text{Dose per administration} = \frac{900 \text{ mg/day}}{2 \text{ administrations/day}} = 450 \text{ mg/administration} $$ The required dose per administration is $\boxed{\text{450 mg}}$. --- b) What is the total volume of suspension required? Step 1: Calculate the total amount of drug needed for the entire 7-day course. $$ \text{Total drug needed} = \text{Total daily dose} \times \text{Duration} $$ $$ \text{Total drug needed} = 900 \text{ mg/day} \times 7 \text{ days} = 6300 \text{ mg} $$ Step 2: Determine the concentration of the suspension in mg/mL. $$ \text{Suspension concentration} = \frac{250 \text{ mg}}{5 \text{ mL}} = 50 \text{ mg/mL} $$ Step 3: Calculate the total volume of suspension required. $$ \text{Total volume of suspension} = \frac{\text{Total drug needed}}{\text{Suspension concentration}} $$ $$ \text{Total volume of suspension} = \frac{6300 \text{ mg}}{50 \text{ mg/mL}} = 126 \text{ mL} $$ The total volume of suspension required is $\boxed{\text{126 mL}}$. --- c) How many 500 mg tablets are needed to compound this? Step 1: Use the total amount of drug needed for the entire course, calculated in part b. $$ \text{Total drug needed} = 6300 \text{ mg} $$ Step 2: Calculate the number of tablets required based on the tablet strength. $$ \text{Number of tablets} = \frac{\text{Total drug needed}}{\text{Tablet strength}} $$ $$ \text{Number of tablets} = \frac{6300 \text{ mg}}{500 \text{ mg/tablet}} = 12.6 \text{ tablets} $$ The number of 500 mg tablets needed to compound the suspension is $\boxed{\text{12.6 tablets}}$.

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