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Give the major product(s) of the following reactions: i) Tetrahydrofuran + H2NNH2/OH-
Chemistry
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Here are the answers to questions 5 and 6:
5. Give the major product(s) of the following reactions
- i)
- Explanation: The substrate is tetrahydrofuran, a stable cyclic ether. Ethers are generally unreactive towards hydrazine () under basic conditions (). However, the reagent combination is characteristic of the Wolff-Kishner reduction, which is used to reduce ketones and aldehydes to alkanes. It is highly probable that the substrate was intended to be a cyclic ketone (e.g., cyclopentanone) for this reaction. Assuming the
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